The fastest knockout in UFC flyweight history is Dustin Ortiz vs Hector Sandoval, at 15 seconds, at UFC Fight Night: Pettis vs. Moreno on 5 August 2017.
| # | Time | Bout | Result | Ended | Date | Event |
|---|---|---|---|---|---|---|
| 1 | 0:15 | Dustin Ortiz vs Hector Sandoval | Dustin Ortiz · KO/TKO | R1 0:15 | 2017-08-05 | UFC Fight Night: Pettis vs. Moreno |
| 2 | 0:17 | Shannon Ross vs Jesus Aguilar | Jesus Aguilar · KO/TKO | R1 0:17 | 2023-07-08 | UFC 290: Volkanovski vs. Rodriguez |
| 3 | 0:26 | Alexandre Pantoja vs Joshua Vantitle | Joshua Van · KO/TKO | R1 0:26 | 2025-12-06 | UFC 323: Dvalishvili vs. Yan 2 |
| 4 | 0:32 | Henry Cejudo vs TJ Dillashawtitle | Henry Cejudo · KO/TKO | R1 0:32 | 2019-01-19 | UFC Fight Night: Cejudo vs. Dillashaw |
| 5 | 0:44 | Yao Zhikui vs Fredy Serrano | Fredy Serrano · KO/TKO | R1 0:44 | 2015-11-28 | UFC Fight Night: Henderson vs Masvidal |
| 6 | 0:44 | Sumudaerji vs Malcolm Gordon | Sumudaerji · KO/TKO | R1 0:44 | 2020-11-28 | UFC Fight Night: Smith vs. Clark |
| 7 | 0:59 | Shannon Ross vs Kleydson Rodrigues | Kleydson Rodrigues · KO/TKO | R1 0:59 | 2023-02-11 | UFC 284: Makhachev vs. Volkanovski |
| 8 | 1:00 | Bruno Silva vs Victor Rodriguez | Bruno Silva · KO/TKO | R1 1:00 | 2021-05-22 | UFC Fight Night: Font vs. Garbrandt |
| 9 | 1:01 | Ode Osbourne vs Zarrukh Adashev | Ode Osbourne · KO/TKO | R1 1:01 | 2022-06-04 | UFC Fight Night: Volkov vs. Rozenstruik |
| 10 | 1:01 | Jake Hadley vs Malcolm Gordon | Jake Hadley · KO/TKO | R1 1:01 | 2023-03-18 | UFC 286: Edwards vs. Usman 3 |
| 11 | 1:08 | JP Buys vs Cody Durden | Cody Durden · KO/TKO | R1 1:08 | 2022-06-25 | UFC Fight Night: Tsarukyan vs. Gamrot |
| 12 | 1:22 | Malcolm Gordon vs Denys Bondar | Malcolm Gordon · KO/TKO | R1 1:22 | 2022-02-05 | UFC Fight Night: Hermansson vs. Strickland |
| 13 | 1:36 | Darrell Montague vs Willie Gates | Willie Gates · KO/TKO | R1 1:36 | 2015-07-12 | The Ultimate Fighter: American Top Team vs. Blackzilians Finale |
| 14 | 1:38 | John Moraga vs Bibulatov Magomed | John Moraga · KO/TKO | R1 1:38 | 2017-10-07 | UFC 216: Ferguson vs. Lee |
| 15 | 2:08 | Demetrious Johnson vs Joseph Benavideztitle | Demetrious Johnson · KO/TKO | R1 2:08 | 2013-12-14 | UFC on FOX: Johnson vs. Benavidez 2 |
| 16 | 2:09 | Brandon Royval vs Matheus Nicolau | Brandon Royval · KO/TKO | R1 2:09 | 2023-04-15 | UFC Fight Night: Holloway vs. Allen |
| 17 | 2:49 | Demetrious Johnson vs Henry Cejudotitle | Demetrious Johnson · KO/TKO | R1 2:49 | 2016-04-23 | UFC 197: Jones vs Saint Preux |
| 18 | 2:50 | CJ Vergara vs Ramazan Temirov | Ramazan Temirov · KO/TKO | R1 2:50 | 2024-10-12 | UFC Fight Night: Royval vs. Taira |
| 19 | 2:51 | Phil Harris vs John Lineker | John Lineker · KO/TKO | R1 2:51 | 2013-10-26 | UFC Fight Night: Machida vs Munoz |
| 20 | 2:58 | Wilson Reis vs Alexandre Pantoja | Alexandre Pantoja · KO/TKO | R1 2:58 | 2019-04-13 | UFC 236: Holloway vs. Poirier 2 |
| 21 | 2:59 | Ode Osbourne vs Tyson Nam | Tyson Nam · KO/TKO | R1 2:59 | 2022-08-13 | UFC Fight Night: Vera vs. Cruz |
| 22 | 3:07 | Joseph Benavidez vs Jussier Formiga | Joseph Benavidez · KO/TKO | R1 3:07 | 2013-09-04 | UFC Fight Night: Teixeira vs Bader |
| 23 | 3:16 | Alex Perez vs Charles Johnsongraded call | Alex Perez · KO/TKO | R1 3:16 | 2026-01-24 | UFC 324: Gaethje vs. Pimblett |
| 24 | 3:18 | Brandon Royval vs Manel Kape | Manel Kape · KO/TKO | R1 3:18 | 2025-12-13 | UFC Fight Night: Royval vs. Kape |
| 25 | 3:21 | Kai Kara-France vs Cody Garbrandt | Kai Kara-France · KO/TKO | R1 3:21 | 2021-12-11 | UFC 269: Oliveira vs. Poirier |
| 26 | 3:39 | Daniel Lacerda vs Victor Altamirano | Victor Altamirano · KO/TKO | R1 3:39 | 2022-08-20 | UFC 278: Usman vs. Edwards |
| 27 | 3:46 | John Moraga vs Ulysses Gomez | John Moraga · KO/TKO | R1 3:46 | 2012-08-04 | UFC on FOX: Shogun vs Vera |
| 28 | 3:46 | Alex Perez vs Jose Torres | Alex Perez · KO/TKO | R1 3:46 | 2018-08-04 | UFC 227: Dillashaw vs. Garbrandt 2 |
| 29 | 3:48 | Kyoji Horiguchi vs Jon Delos Reyes | Kyoji Horiguchi · KO/TKO | R1 3:48 | 2014-09-20 | UFC Fight Night: Hunt vs Nelson |
| 30 | 3:49 | Dustin Ortiz vs Matheus Nicolau | Dustin Ortiz · KO/TKO | R1 3:49 | 2018-07-28 | UFC Fight Night: Alvarez vs. Poirier 2 |
| 31 | 4:02 | Manel Kape vs Zhalgas Zhumagulov | Manel Kape · KO/TKO | R1 4:02 | 2021-12-04 | UFC Fight Night: Font vs. Aldo |
| 32 | 4:04 | Kai Kara-France vs Steve Erceg | Kai Kara-France · KO/TKO | R1 4:04 | 2024-08-17 | UFC 305: Du Plessis vs. Adesanya |
| 33 | 4:06 | Jussier Formiga vs Alex Perez | Alex Perez · KO/TKO | R1 4:06 | 2020-06-06 | UFC 250: Nunes vs. Spencer |
| 34 | 4:13 | John Dodson vs Darrell Montague | John Dodson · KO/TKO | R1 4:13 | 2013-10-19 | UFC 166: Velasquez vs Dos Santos 3 |
| 35 | 4:17 | Alexandre Pantoja vs Matt Schnell | Alexandre Pantoja · KO/TKO | R1 4:17 | 2019-12-21 | UFC Fight Night: Edgar vs. The Korean Zombie |
| 36 | 4:19 | Joseph Benavidez vs Alex Perez | Joseph Benavidez · KO/TKO | R1 4:19 | 2018-11-30 | The Ultimate Fighter: Heavy Hitters Finale |
| 37 | 4:21 | Steve Erceg vs Ramazan Temirovgraded call | Ramazan Temirov · KO/TKO | R1 4:21 | 2026-07-25 | UFC Fight Night: Ankalaev vs. Guskov |
| 38 | 4:24 | Hector Sandoval vs Matt Schnell | Hector Sandoval · KO/TKO | R1 4:24 | 2017-04-22 | UFC Fight Night: Swanson vs. Lobov |
| 39 | 4:33 | Charles Johnson vs Jimmy Flick | Charles Johnson · KO/TKO | R1 4:33 | 2023-01-14 | UFC Fight Night: Strickland vs. Imavov |
| 40 | 4:40 | Nate Maness vs Mateus Mendonca | Nate Maness · KO/TKO | R1 4:40 | 2023-10-07 | UFC Fight Night: Dawson vs. Green |
| 41 | 4:43 | Richie Vaculik vs Justin Scoggins | Justin Scoggins · KO/TKO | R1 4:43 | 2013-12-06 | UFC Fight Night: Hunt vs Bigfoot |
| 42 | 4:44 | Manel Kape vs Ode Osbourne | Manel Kape · KO/TKO | R1 4:44 | 2021-08-07 | UFC 265: Lewis vs. Gane |
| 43 | 4:55 | Rogerio Bontorin vs Kai Kara-France | Kai Kara-France · KO/TKO | R1 4:55 | 2021-03-06 | UFC 259: Blachowicz vs. Adesanya |
| 44 | 4:59 | Alptekin Ozkilic vs Ben Nguyen | Ben Nguyen · KO/TKO | R1 4:59 | 2015-05-09 | UFC Fight Night: Miocic vs Hunt |
| 45 | 4:59 | Brandon Moreno vs Brandon Royval | Brandon Moreno · KO/TKO | R1 4:59 | 2020-11-21 | UFC 255: Figueiredo vs. Perez |
| 46 | 5:11 | Joseph Benavidez vs Yasuhiro Urushitani | Joseph Benavidez · KO/TKO | R2 0:11 | 2012-03-02 | UFC on FX: Alves vs Kampmann |
| 47 | 5:11 | Cody Durden vs Jose Ochoa | Jose Ochoa · KO/TKO | R2 0:11 | 2025-06-14 | UFC Fight Night: Usman vs. Buckley |
| 48 | 5:25 | Henry Cejudo vs Wilson Reis | Henry Cejudo · KO/TKO | R2 0:25 | 2017-09-09 | UFC 215: Nunes vs Shevchenko 2 |
| 49 | 5:26 | Matt Schnell vs Steve Erceg | Steve Erceg · KO/TKO | R2 0:26 | 2024-03-02 | UFC Fight Night: Rozenstruik vs. Gaziev |
| 50 | 5:46 | Jeff Molina vs Daniel Lacerda | Jeff Molina · KO/TKO | R2 0:46 | 2021-10-23 | UFC Fight Night: Costa vs. Vettori |
| 51 | 5:55 | Tatsuro Taira vs Carlos Hernandez | Tatsuro Taira · KO/TKO | R2 0:55 | 2023-12-09 | UFC Fight Night: Song vs. Gutierrez |
| 52 | 6:03 | John Lineker vs Jose Maria | John Lineker · KO/TKO | R2 1:03 | 2013-08-03 | UFC 163: Aldo vs Jung |
| 53 | 6:03 | Jimmy Flick vs Alessandro Costa | Alessandro Costa · KO/TKO | R2 1:03 | 2023-06-17 | UFC Fight Night: Vettori vs. Cannonier |
| 54 | 6:07 | John Lineker vs Azamat Gashimov | John Lineker · KO/TKO | R2 1:07 | 2013-05-18 | UFC on FX: Belfort vs. Rockhold |
| 55 | 6:34 | Sergio Pettis vs Ryan Benoit | Ryan Benoit · KO/TKO | R2 1:34 | 2015-03-14 | UFC 185: Pettis vs Dos Anjos |
| 56 | 6:35 | Alessandro Costa vs Kevin Borjas | Alessandro Costa · KO/TKO | R2 1:35 | 2024-05-04 | UFC 301: Pantoja vs. Erceg |
| 57 | 6:44 | Matheus Nicolau vs Matt Schnell | Matheus Nicolau · KO/TKO | R2 1:44 | 2022-12-03 | UFC Fight Night: Thompson vs. Holland |
| 58 | 6:54 | Joseph Benavidez vs Deiveson Figueiredo | Deiveson Figueiredo · KO/TKO | R2 1:54 | 2020-02-29 | UFC Fight Night: Benavidez vs. Figueiredo |
| 59 | 6:54 | Ode Osbourne vs Luis Gurule | Ode Osbourne · KO/TKO | R2 1:54 | 2025-04-05 | UFC Fight Night: Emmett vs. Murphy |
| 60 | 7:16 | Matheus Nicolau vs Alex Perez | Alex Perez · KO/TKO | R2 2:16 | 2024-04-27 | UFC Fight Night: Nicolau vs. Perez |
| 61 | 7:24 | Brandon Moreno vs Tatsuro Taira | Tatsuro Taira · KO/TKO | R2 2:24 | 2025-12-06 | UFC 323: Dvalishvili vs. Yan 2 |
| 62 | 7:28 | Bilal Hasan vs Nilson Rojasgraded call | Bilal Hasan · KO/TKO | R2 2:28 | 2026-08-29 | UFC Fight Night: Nurmagomedov vs. Song |
| 63 | 7:55 | Jarred Brooks vs Jose Torres | Jose Torres · KO/TKO | R2 2:55 | 2018-06-01 | UFC Fight Night: Rivera vs. Moraes |
| 64 | 7:56 | Bruno Silva vs JP Buys | Bruno Silva · KO/TKO | R2 2:56 | 2021-03-20 | UFC Fight Night: Brunson vs. Holland |
| 65 | 7:58 | Cody Durden vs Bruno Silva | Bruno Silva · KO/TKO | R2 2:58 | 2024-07-20 | UFC Fight Night: Lemos vs. Jandiroba |
| 66 | 7:59 | Alex Perez vs Tatsuro Taira | Tatsuro Taira · KO/TKO | R2 2:59 | 2024-06-15 | UFC Fight Night: Perez vs. Taira |
| 67 | 8:08 | John Moraga vs Deiveson Figueiredo | Deiveson Figueiredo · KO/TKO | R2 3:08 | 2018-08-25 | UFC Fight Night: Gaethje vs. Vick |
| 68 | 8:59 | HyunSung Park vs Shannon Ross | HyunSung Park · KO/TKO | R2 3:59 | 2023-12-09 | UFC Fight Night: Song vs. Gutierrez |
| 69 | 9:04 | CJ Vergara vs Daniel Lacerda | CJ Vergara · KO/TKO | R2 4:04 | 2023-03-25 | UFC Fight Night: Vera vs. Sandhagen |
| 70 | 9:21 | Imanol Rodriguez vs Kevin Borjasgraded call | Imanol Rodriguez · KO/TKO | R2 4:21 | 2026-02-28 | UFC Fight Night: Moreno vs. Kavanagh |
| 71 | 9:28 | Joby Sanchez vs Geane Herrera | Geane Herrera · KO/TKO | R2 4:28 | 2015-12-11 | The Ultimate Fighter: Team McGregor vs. Team Faber Finale |
| 72 | 9:31 | Iliarde Santos vs Chris Cariaso | Chris Cariaso · KO/TKO | R2 4:31 | 2013-10-09 | UFC Fight Night: Maia vs Shields |
| 73 | 9:31 | Joshua Van vs Felipe Bunes | Joshua Van · KO/TKO | R2 4:31 | 2024-01-13 | UFC Fight Night: Ankalaev vs. Walker 2 |
| 74 | 9:34 | Deiveson Figueiredo vs Joseph Morales | Deiveson Figueiredo · KO/TKO | R2 4:34 | 2018-02-03 | UFC Fight Night: Machida vs. Anders |
| 75 | 9:35 | John Dodson vs Jussier Formiga | John Dodson · KO/TKO | R2 4:35 | 2012-10-05 | UFC on FX: Browne vs Bigfoot |
| 76 | 9:35 | Charles Johnson vs Lone'er Kavanagh | Charles Johnson · KO/TKO | R2 4:35 | 2025-08-23 | UFC Fight Night: Walker vs. Zhang |
| 77 | 9:41 | Louis Smolka vs Ben Nguyen | Louis Smolka · KO/TKO | R2 4:41 | 2016-07-13 | UFC Fight Night: McDonald vs. Lineker |
| 78 | 9:42 | Mark De La Rosa vs Raulian Paiva | Raulian Paiva · KO/TKO | R2 4:42 | 2020-02-15 | UFC Fight Night: Anderson vs. Blachowicz |
| 79 | 9:47 | Jussier Formiga vs Joseph Benavidez | Joseph Benavidez · KO/TKO | R2 4:47 | 2019-06-29 | UFC Fight Night: Ngannou vs. Dos Santos |
| 80 | 9:50 | Joseph Benavidez vs Darren Uyenoyama | Joseph Benavidez · KO/TKO | R2 4:50 | 2013-04-20 | UFC on FOX: Henderson vs Melendez |
| 81 | 9:56 | Alessandro Costa vs Stewart Nicollgraded call | Alessandro Costa · KO/TKO | R2 4:56 | 2026-04-04 | UFC Fight Night: Moicano vs. Duncan |
| 82 | 10:00 | Marco Beltran vs Deiveson Figueiredo | Deiveson Figueiredo · KO/TKO | R2 5:00 | 2017-06-03 | UFC 212: Aldo vs. Holloway |
| 83 | 10:18 | Richie Vaculik vs Louis Smolka | Louis Smolka · KO/TKO | R3 0:18 | 2014-11-07 | UFC Fight Night: Rockhold vs Bisping |
| 84 | 10:20 | Joshua Van vs Charles Johnson | Charles Johnson · KO/TKO | R3 0:20 | 2024-07-13 | UFC Fight Night: Namajunas vs. Cortez |
| 85 | 10:47 | Alessandro Costa vs Alden Coria | Alden Coria · KO/TKO | R3 0:47 | 2025-09-13 | UFC Fight Night: Lopes vs. Silva |
| 86 | 11:34 | Bentley Syler vs Fredy Serrano | Fredy Serrano · KO/TKO | R3 1:34 | 2015-03-21 | UFC Fight Night: Maia vs LaFlare |
| 87 | 11:57 | Manel Kape vs Bruno Silva | Manel Kape · KO/TKO | R3 1:57 | 2024-12-14 | UFC Fight Night: Covington vs. Buckley |
| 88 | 12:13 | Amir Albazi vs Alessandro Costa | Amir Albazi · KO/TKO | R3 2:13 | 2022-12-17 | UFC Fight Night: Cannonier vs. Strickland |
| 89 | 12:16 | Manel Kape vs Asu Almabayev | Manel Kape · KO/TKO | R3 2:16 | 2025-03-01 | UFC Fight Night: Kape vs. Almabayev |
| 90 | 12:38 | Ryan Benoit vs Ashkan Mokhtarian | Ryan Benoit · KO/TKO | R3 2:38 | 2017-11-18 | UFC Fight Night: Werdum vs. Tybura |
| 91 | 12:42 | Manel Kape vs Kyoji Horiguchigraded call | Manel Kape · KO/TKO | R3 2:42 | 2026-06-20 | UFC Fight Night: Kape vs. Horiguchi |
| 92 | 12:58 | Dustin Ortiz vs Willie Gates | Dustin Ortiz · KO/TKO | R3 2:58 | 2015-08-08 | UFC Fight Night: Teixeira vs Saint Preux |
| 93 | 13:19 | Jose Maria vs Dustin Ortiz | Dustin Ortiz · KO/TKO | R3 3:19 | 2013-11-09 | UFC Fight Night: Belfort vs Henderson 2 |
| 94 | 13:28 | Marcos Vinicius vs Ali Bagautinov | Ali Bagautinov · KO/TKO | R3 3:28 | 2013-09-04 | UFC Fight Night: Teixeira vs Bader |
| 95 | 14:01 | Bruno Silva vs Joshua Van | Joshua Van · KO/TKO | R3 4:01 | 2025-06-07 | UFC 316: Dvalishvili vs. O'Malley 2 |
| 96 | 14:34 | Brandon Moreno vs Kai Kara-Francetitle | Brandon Moreno · KO/TKO | R3 4:34 | 2022-07-30 | UFC 277: Pena vs. Nunes 2 |
| 97 | 14:51 | John Lineker vs Alptekin Ozkilic | John Lineker · KO/TKO | R3 4:51 | 2014-07-16 | UFC Fight Night: Cowboy vs Miller |
| 98 | 21:32 | Joshua Van vs Tatsuro Tairatitlegraded call | Joshua Van · KO/TKO | R5 1:32 | 2026-05-09 | UFC 328: Chimaev vs. Strickland |